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→Diagnosis
===Clinical Signs===
===Clinical Signs===
In sheep, fasciolosis may present as acute or chronic manifestations. Acute fasciolosis usually occurs between September and December and is caused by large numbers of immature ''[[Fasciola hepatica]]'' migrating through the liver parenchyma and causing massive damage. If sheep are not exposed to at-risk pasture until later in the year, acute fasciolosis may occur as late as the following Feburary. Hepatic damage caused by migration of fluke larvae gives clinical signs including lethargy, pallor, dyspnoea and death in both young and adult animals. Handling of sheep may cause liver rupture and sudden death, and sudden death may also occur due to Black's disease (''Clostridium novyi'' type B) or bacillary haemoglobinuria (''Clostridium novyi'' type D) in unvaccinated sheep. This is a result of larval migrationg facilitiating the activation of clostridial spores. A more subtle, sub-acute presentation is also possible, which is characterised by significant weight loss over one to two weeks, a normochromic anaemia and an enlarged, haemorrhagic liver.
'''Acute fasciolosis'''
'''Chronic fasciolosis'''
'''Chronic fasciolosis'''
#Reduced weight-gain and/or wool growth and/or milk production
#Reduced weight-gain and/or wool growth and/or milk production
#Loss of body tissue (i.e. weight-loss); hypoalbuminaemia → reduced plasma oncotic pressure → oedema
#Loss of body tissue (i.e. weight-loss); hypoalbuminaemia → reduced plasma oncotic pressure → oedema
==Treatment==
==Treatment==