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For instance, wet summers increase both the number of snail habitats and the hatching of fluke eggs, leading to many infected snails. These in turn shed many cercariae, which form a high density of metacercariae on herbage to increase the risk of fasciolosis. Conversely, in dry summers, fewer fluke eggs hatch and snails are restricted to their permanent habitats. Fewer snails become infected and cercariae and metacercariae numbers are low and confined to the areas where snails can survive. The risk of fasciolosis is therefore reduced.
 
For instance, wet summers increase both the number of snail habitats and the hatching of fluke eggs, leading to many infected snails. These in turn shed many cercariae, which form a high density of metacercariae on herbage to increase the risk of fasciolosis. Conversely, in dry summers, fewer fluke eggs hatch and snails are restricted to their permanent habitats. Fewer snails become infected and cercariae and metacercariae numbers are low and confined to the areas where snails can survive. The risk of fasciolosis is therefore reduced.
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Upon ingestion, metacercariae  excyst to present as immature  flukes in the  small intestine. These then migrate  across the  peritoneal  cavity over a period of roughly one week, and invade the liver. Larvae continue to migrate within the hepatic parenchyma, beoming more destructive as they grow to a length of up to one centimetre. In about six weeks, immature fluke enter the bile ducts and mature to adults, where they begin to produce eggs. The prepatent period is around ten to twelve weeks.
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In sheep, "acute" disease caused by fluke larvae is the most common presentation, and generally occurs in the wetter Autumn and early Winter months in both lambs and ewes. Fasciolosis in cattle can occur at any time of year and tends to involve adult fluke, causing "chronic" disease.
 
In sheep, "acute" disease caused by fluke larvae is the most common presentation, and generally occurs in the wetter Autumn and early Winter months in both lambs and ewes. Fasciolosis in cattle can occur at any time of year and tends to involve adult fluke, causing "chronic" disease.
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