Changes

 

[[Image:Kidney.jpg|200px|thumb|right|'''Histology of a normal iguana kidney. Note the clearly distinct cells of the glomerulus''' (Copyright © RVC)]]

[[Image:Kidney.jpg|200px|thumb|right|'''Histology of a normal iguana kidney. Note the clearly distinct cells of the glomerulus''' (Copyright © RVC)]]

[[Image:Dis_kid.jpg|200px|thumb|right|'''Histology of an iguana kidney with gout. Note the darker staining tophus and indistinct glomerulus''' (Copyright © RVC)]]

[[Image:Dis_kid.jpg|200px|thumb|right|'''Histology of an iguana kidney with gout. Note the darker staining tophus and indistinct glomerulus''' (Copyright © RVC)]]

   

   

===Examination===

==Examination==

History may indicate husbandry problems such as lack of adequate water or recent treatment with possible nephrotoxic drugs. The presenting complaint is usually non-specific such as anorexia, weight loss, tremors, lethargy, flaccid paresis, distended abdomen and constipation. Physical examination may reveal nephromegaly (one or more lumps in the caudal third; in lizards, it may be palpable anterior to the pelvis or per [[Cloaca|cloaca]]) but there is often nothing significant found.

History may indicate husbandry problems such as lack of adequate water or recent treatment with possible nephrotoxic drugs. The presenting complaint is usually non-specific such as anorexia, weight loss, tremors, lethargy, flaccid paresis, distended abdomen and constipation. Physical examination may reveal nephromegaly (one or more lumps in the caudal third; in lizards, it may be palpable anterior to the pelvis or per [[Cloaca|cloaca]]) but there is often nothing significant found.

===Diagnosis===

==Diagnosis==

Diagnosis of renal disease may be suspected on history and physical examination. Diagnosis includes the following:=

Diagnosis of renal disease may be suspected on history and physical examination. Diagnosis includes the following:=

===Therapy===

==Therapy==

Correct diet and environmental conditions may limit the progression of the disease. Consider a low [[Phosphorus|phosphorus]] diet. Supportive therapy is especially important since there is often no specific treatment. The most important factors include fluid therapy and being kept within the [[Preferred optimum temperature zone|POTZ]]. Allopurinol and phosphate binders have been advised but are often ineffective.

Correct diet and environmental conditions may limit the progression of the disease. Consider a low [[Phosphorus|phosphorus]] diet. Supportive therapy is especially important since there is often no specific treatment. The most important factors include fluid therapy and being kept within the [[Preferred optimum temperature zone|POTZ]]. Allopurinol and phosphate binders have been advised but are often ineffective.

[[Lizard and Snake Euthanasia|Euthanasia]] is often the final outcome.

[[Lizard and Snake Euthanasia|Euthanasia]] is often the final outcome.

===Prevention===

==Prevention==

As with [[Lizard Metabolic Bone Disease|metabolic bone disease (MBD)]], appropriate housing and diet will help with prevention.=

As with [[Lizard Metabolic Bone Disease|metabolic bone disease (MBD)]], appropriate housing and diet will help with prevention.=