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==Pathology==
 
==Pathology==
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[[Image:Adenovirus  pneumonia.jpg|right|thumb|100px|<small><center>Adenovirus  pneumonia (Image sourced from Bristol Biomed Image Archive with  permission)</center></small>]]
    
Subclinical infection with canine adenovirus 1 most typically causes a mild bronchointerstitial pneumonia, although a necrotising bronchiolitis  may occur in immunocompromised dogs. This is seen histologcally as  necrosis of the bronchiolar and alveolar epithelium, pulmonary oedema  and hyperplasia of type II pneumocytes.  
 
Subclinical infection with canine adenovirus 1 most typically causes a mild bronchointerstitial pneumonia, although a necrotising bronchiolitis  may occur in immunocompromised dogs. This is seen histologcally as  necrosis of the bronchiolar and alveolar epithelium, pulmonary oedema  and hyperplasia of type II pneumocytes.  
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In [[Infectious Canine Hepatitis]], canine adenovirus 1 principally causes damage to the endothelium and to hepatic cells. Endothelial damage results in widespread petechial haemorrhages, and hepatic damage may be visualised as an enlarged liver, mottled with areas of necrosis. Microscopically, centrolobular necrosis is seen in the liver, and adenoviral nuclear inclusion  bodies may be observed in Kupffer and parencymal cells. Glomerulonephritis and occular pathology are not uncommon findings.
 
In [[Infectious Canine Hepatitis]], canine adenovirus 1 principally causes damage to the endothelium and to hepatic cells. Endothelial damage results in widespread petechial haemorrhages, and hepatic damage may be visualised as an enlarged liver, mottled with areas of necrosis. Microscopically, centrolobular necrosis is seen in the liver, and adenoviral nuclear inclusion  bodies may be observed in Kupffer and parencymal cells. Glomerulonephritis and occular pathology are not uncommon findings.
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