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765 bytes added ,  10:52, 7 August 2010
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Fair in cases that are rapidly treated but poor in foals with evidence of hypovolaemia and septic shock.  Surgical cases also carry a poorer prognosis than cases which are resolved medically.<ref name="Merck">Merck & Co (2008) '''The Merck Veterinary Manual (Eighth Edition)''', ''Merial''.</ref>  In a recent study, long term survival of 25 affected horses was 33%.<ref name="Cribb">Cribb, N.C, Cote, N.M, Boure, L.P, Peregrine, A.S (2006) Acute small intestinal obstruction associated with ''Parascaris equorum'' infection in young horses: 25 cases (9185-2004).  ''N Z Vet J'', 54:338-343.  In: Blikslager, A.T (2010) ''Obstructive Disorders of the Gastrointestinal Tract'' in Reed, S.M, Bayly, W.M. and Sellon, D.C (2010) '''Equine Internal Medicine''' (Third Edition), Chapter 15, ''Saunders''.</ref>:  Failure to relieve the impaction may lead to intestinal rupture.<ref name="Merck">Merck & Co (2008) '''The Merck Veterinary Manual (Eighth Edition)''', ''Merial''.</ref>
 
Fair in cases that are rapidly treated but poor in foals with evidence of hypovolaemia and septic shock.  Surgical cases also carry a poorer prognosis than cases which are resolved medically.<ref name="Merck">Merck & Co (2008) '''The Merck Veterinary Manual (Eighth Edition)''', ''Merial''.</ref>  In a recent study, long term survival of 25 affected horses was 33%.<ref name="Cribb">Cribb, N.C, Cote, N.M, Boure, L.P, Peregrine, A.S (2006) Acute small intestinal obstruction associated with ''Parascaris equorum'' infection in young horses: 25 cases (9185-2004).  ''N Z Vet J'', 54:338-343.  In: Blikslager, A.T (2010) ''Obstructive Disorders of the Gastrointestinal Tract'' in Reed, S.M, Bayly, W.M. and Sellon, D.C (2010) '''Equine Internal Medicine''' (Third Edition), Chapter 15, ''Saunders''.</ref>:  Failure to relieve the impaction may lead to intestinal rupture.<ref name="Merck">Merck & Co (2008) '''The Merck Veterinary Manual (Eighth Edition)''', ''Merial''.</ref>
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**Fenbendazole at 5mg/kg PO (lower dose with only 50% efficacy against ''Parasacaris'')
 
**Fenbendazole at 5mg/kg PO (lower dose with only 50% efficacy against ''Parasacaris'')
 
**Followed one week later by a full dose of Fenbendazole at 10mg/kg PO
 
**Followed one week later by a full dose of Fenbendazole at 10mg/kg PO
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Care should be taken to avoid the following practices because they increase the risk of development of resistance and could ultimately result in ineffective therapy:(1) Too frequent and repeated use of anthelmintics from the same class, over an extended period of time.(2) Underdosing, which may be due to underestimation of bodyweight, misadministration of the product, or lack of calibration of the dosing device (if any).Suspected clinical cases of resistance to anthelmintics should be further investigated using appropriate tests (e.g. Faecal Egg Count Reduction Test). Where the results of the test(s) strongly suggest resistance to a  particular anthelmintics belonging to another pharmacological class and having a different mode of action should be used.
 
*Regular faecal worm egg counts should be conducted to monitor the effects of the anthelmintic schedule and the presence of resistance
 
*Regular faecal worm egg counts should be conducted to monitor the effects of the anthelmintic schedule and the presence of resistance
 
*Clean pasture management including the regular removal of faeces
 
*Clean pasture management including the regular removal of faeces
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