6,502
edits
Changes
no edit summary
==Description==
==Description==
'''Feline Parvovirus''', is from the family Parvoviridae, and is also known as '''feline infectious enteritis''' (FIE) or '''feline panleukopenia'''. It is a non-enveloped virus, capable of persisting for long periods of time in the enviroment.
'''Feline Parvovirus''', is from the family Parvoviridae, and is also known as '''feline infectious enteritis''' (FIE) or '''feline panleukopenia'''. It is a non-enveloped virus, capable of persisting for long periods of time in the enviroment.
It infects the lymph nodes of the oropharynx and the nasopharynx, and the spreads to other tissues. It infects and kills actively replicating cells. Kittens are most susceptible, but unvaccinated older cats can also become infected.
It infects the lymph nodes of the oropharynx and the nasopharynx, and the spreads to other tissues. It infects and kills actively replicating cells. Kittens are most susceptible, but unvaccinated older cats can also become infected.
Feline Parvovirus kills the stem cells of the villi. The villi tip cells turnover normally but are not being replaced, leading to stunted villi and malabsorption.
Feline Parvovirus kills the stem cells of the villi. The villi tip cells turnover normally but are not being replaced, leading to stunted villi and malabsorption.
Animals who have contracted the virus usually die despite treatment, due to the extensive dehydration.
Animals who have contracted the virus usually die despite treatment, due to the extensive dehydration.
Infection may be via '''direct contact''' or by '''fomites'''. Subclinical infection may also occur.
==Epidemiology==
==Signalment==
Feline Parvovirus is most commonly seen in '''cats''', but is also seen in minks, racoons, and pandas.
==Diagnosis==
==Diagnosis==
4. Evidence of exposure to virus - detect antibody to virus within the blood.
4. Evidence of exposure to virus - detect antibody to virus within the blood.
===Clinical Signs===
==Control==
===Radiography===
===Biopsy===
===Endoscopy===
===Laboratory Tests===
===Pathology===
==[[Parvovirus Enteritis]]==
===Gross Pathology===
==Gross Pathology==
The virus targets crypt cells and lymphoid areas,causing [[:Category:Enteritis, Villus Atrophy|villus atrophy]]. In the cat, the intestine becomes thickened, turgid and swollen, with a pale, dull and mottled appearance.
The virus targets crypt cells and lymphoid areas,causing [[:Category:Enteritis, Villus Atrophy|villus atrophy]]. In the cat, the intestine becomes thickened, turgid and swollen, with a pale, dull and mottled appearance.
Lower down in the gut, enteritis is apparent. In the cat this is fibrinous enteritis, and in the dog it is haemorrhagic.
Lower down in the gut, enteritis is apparent. In the cat this is fibrinous enteritis, and in the dog it is haemorrhagic.
==Histological Pathology==
===Histological Pathology===
The crypt lining cells undergo complete necrosis, but very little inflammation is seen.
The crypt lining cells undergo complete necrosis, but very little inflammation is seen.
The [[Lymph Nodes - Anatomy & Physiology|Lymph nodes]] appear pale and oedematous, and almost aplastic. The [[Bone Marrow - Anatomy & Physiology|Bone marrow]] appears pale and fatty looking and is depleted of cells.
The [[Lymph Nodes - Anatomy & Physiology|Lymph nodes]] appear pale and oedematous, and almost aplastic. The [[Bone Marrow - Anatomy & Physiology|Bone marrow]] appears pale and fatty looking and is depleted of cells.
==Treatment==
Modified live and inactivated virus vaccines are avaliable, with boosters every 1-2 years required.
One should also try to prevent exposure to kittens with feline panleukopenia.
==Prognosis==
==Links==
==References==