Changes

===Pathology===

===Pathology===

 

Macroscopically, the hair coat is seen to be rough, body condition is poor and there is evidence of severe dehydration. Faecal staining may be suggestive of diarrhoea during life. The intestine itself is oedematous and petechial or ecchymotic haemorrhages may be seens on the serosal or mucosal surfaces of the jejunum and ileum. Thymic atrophy is apparent and the bone marrow is gelatinous or liquid in texture. Animals infected ''in utero'' or neonatally nay show gross hypoplasia of the cerebellum,

The virus targets crypt cells and lymphoid areas,causing [[:Category:Enteritis, Villus Atrophy|villus atrophy]].  In the cat, the intestine becomes thickened, turgid and swollen, with a pale, dull and mottled appearance.  

 

The contents appear rather dry, and this becomes increasingly evident lower down the gut.

 

Lower down in the gut, enteritis is apparent. In the cat this is fibrinous enteritis, and in the dog it is haemorrhagic.