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Materno-Fetal Immunity - Introduction (view source)
Revision as of 12:57, 10 August 2010
, 12:57, 10 August 2010no edit summary
Passive immunity occurs when 'preformed' antibodies are made in one animal and passed onto another. For example a cow passes on her own antibodies to her calf via colostrum (first milk after parturition) and milk.
Passive immunity occurs when 'preformed' antibodies are made in one animal and passed onto another. For example a cow passes on her own antibodies to her calf via colostrum (first milk after parturition) and milk.
** Vitamins and minerals.
** Vitamins and minerals.
*[[Immunoglobulin G|IgG]] is most abudant in colostrum, followed by [[Immunoglobulin A|[[IgA]]]] and [[Immunoglobulin M|IgM]]
*[[Immunoglobulin G|IgG]] is most abudant in colostrum, followed by [[Immunoglobulin A|[[IgA]]]] and [[Immunoglobulin M|IgM]]
* During the first 30 hours of life, [[Immunoglobulins|immunoglobulins]] are absorbed through the intact [[Jejunum - Anatomy & Physiology|jejunum]] and pass to the [[lacteals]], [[Lymphatic Vessels - Anatomy & Physiology|thoracic duct]] and into the systemic circulation.
* During the first 30 hours of life, [[Immunoglobulins|immunoglobulins]] are absorbed through the intact [[Jejunum - Anatomy & Physiology|jejunum]] and pass to the lacteals, [[Lymphatic Vessels - Anatomy & Physiology|thoracic duct]] and into the systemic circulation.
* The first diagram (entitled Transfer of [[Immunoglobulin G|IgG]] across intestine via FcRn) shows [[Immunoglobulin G|IgG]] being present in the intestine of a neonate, from the ingestion of colostrum. Fc receptors (FcRn) are present on the surface of the intestinal epithelial cell in neonates for the first 30 hours. The [[Immunoglobulin G|IgG]] binds to the receptors and is transported through the cell by pinocytosis and released into the lacteals unchanged.
* The first diagram (entitled Transfer of [[Immunoglobulin G|IgG]] across intestine via FcRn) shows [[Immunoglobulin G|IgG]] being present in the intestine of a neonate, from the ingestion of colostrum. Fc receptors (FcRn) are present on the surface of the intestinal epithelial cell in neonates for the first 30 hours. The [[Immunoglobulin G|IgG]] binds to the receptors and is transported through the cell by pinocytosis and released into the lacteals unchanged.
* The capacity for immunoglobulin absorption progressively declines from birth due to the FcRn only being present for a limited period of time. After 6 hours a third of the FcRn are non functional.
* The capacity for immunoglobulin absorption progressively declines from birth due to the FcRn only being present for a limited period of time. After 6 hours a third of the FcRn are non functional.