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==Introduction==
 
==Introduction==
 
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[[File:Adenovirus.jpg|thumb|250px|right]]
    
Canine Adenovirus 1 (CAV-1) was first isolated by Carbasso in 1954<sup>1</sup> from a case of acute hepatitis in the dog. This virus found to be identical to the virus isolated in 1947 by Rubarth<sup>2</sup> from a dog showing acute liver lesions, and so CAV-1 was originally known as Infectious Canine Hepatitis (ICH) virus. Subsequently, CAV1 infection was shown to be common in young dogs worldwide, with 82% of British dogs displaying neutralising antibody titres by nine months of age<sup>3</sup>. It has also since been demonstrated that CAV1 has a role in diseases other than [[Infectious Canine Hepatitis]], such as [[Canine Infectious Tracheobronchitis]].
 
Canine Adenovirus 1 (CAV-1) was first isolated by Carbasso in 1954<sup>1</sup> from a case of acute hepatitis in the dog. This virus found to be identical to the virus isolated in 1947 by Rubarth<sup>2</sup> from a dog showing acute liver lesions, and so CAV-1 was originally known as Infectious Canine Hepatitis (ICH) virus. Subsequently, CAV1 infection was shown to be common in young dogs worldwide, with 82% of British dogs displaying neutralising antibody titres by nine months of age<sup>3</sup>. It has also since been demonstrated that CAV1 has a role in diseases other than [[Infectious Canine Hepatitis]], such as [[Canine Infectious Tracheobronchitis]].
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