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Category:Spleen - Pathology (view source)
Revision as of 13:39, 11 August 2010
, 13:39, 11 August 2010no edit summary
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+''NB:Be aware of age-related changes regarding the spleen''+==Splenic Lesions==
===Splenitis===+
−===Anthrax===+===Torsion===+
−===Haemolytic Anaemia===+===Chronic Venous Congestion===+
+
+
+===Barbituates===+
+===Splenic Tumours===+
−*these are important surgically since splenomegaly can be diagnoses clinically by palpation or X-ray and some are surgically curable+====Hyperplastic Nodules or Benign Lymphoma====+
−*very common incidental findings in older dogs
−*should not be mistakenly identified as pathognomic lesions
−*consist of nodules of hyperplastic white and red pulp
−:- usually 1-2 cms in size, but occasionally may be larger
−:- spherical
−:- protrude hemispherically from the surface as yellow and red mottled nodules
−*infrequently, may rupture and give rise to haemorrhage
−====Haemangioma====
−*benign tumour of dogs
−*may grow to considerable size
−:- the size of the lesion giving rise to clinical signs is compounded by haemorrhage from and into the tumour
−:- thus, a large mass of apple size may be found protruding from the spleen and adherent to the omentum
−*on section, it is largely blood clot
−*responds well to surgery
−:- therefore it must be distinguished from haemangiosarcoma
−====Haemangiosarcoma====
−*highly malignant tumour of dogs
−*distinguished from the superficially similar haemangioma by the presence of much more formed, solid tumour tissue
−*accurate prognosis demands histological examination
−*secondaries are common locally in the [[Peritoneal cavity - Anatomy & Physiology#Omentum|omentum]] and in the [[Liver - Anatomy & Physiology|liver]]
−:- course is usually short, often only a month or two
−:- metastases may occur in almost every organ
−====Haematopoietic Neoplasms====
−=====lymphosarcoma=====
−* splenomegaly occurs in multicentric lymphosarcoma
−*splenic enlargement may be marked if any form of lymphosarcoma is in leukaemic phase
−=====myeloid (granulocytic) leukaemia=====
−*rare
−*all species
−*extreme form with spleen approaching liver size
−=====systemic mastocytosis=====
−*cat
−*extreme form with spleen approaching liver size
''NB:Be aware of age-related changes regarding the spleen''
−Splenic Lesions
−*splenomegaly is the main clinical finding associated with the spleen in disease
*splenomegaly is the main clinical finding associated with the spleen in disease
−Splenitis
−[[Anthrax]]
−[[Splenic Torsion]]
+[[Haemolytic Anaemia]]
+Chronic Venous Congestion
*this may be seen along with chronic venous congestion of the liver in cases of chronic cardiac failure
*this may be seen along with chronic venous congestion of the liver in cases of chronic cardiac failure
−Barbituates
* administration of barbituates can produce a degree of splenomegaly due to splenic engorgement by erythrocytes
* administration of barbituates can produce a degree of splenomegaly due to splenic engorgement by erythrocytes
−[[Splenic Neoplasia]]
−===Infarction===
===Infarction===
===Rupture===
===Rupture===