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Sub-total colectomy can be used to correct megacolon in the cat. However, this technique is very poorly tolerated in the dog. The term refers to the removal of the majority of the colon, and the ileocaecocolic valve may be preserved or removed. The ileocaecocolic valve prevents reflux of colonic contents into the small intestine and so some surgeons believe that removing this structure can predispose to small intestinal bacterial overgrowth,steatorrhoea and deconjugation of bile salts<sup>2</sup>. However, removing the ileocaecocolic valve minimises the recurrence of megacolon.  
 
Sub-total colectomy can be used to correct megacolon in the cat. However, this technique is very poorly tolerated in the dog. The term refers to the removal of the majority of the colon, and the ileocaecocolic valve may be preserved or removed. The ileocaecocolic valve prevents reflux of colonic contents into the small intestine and so some surgeons believe that removing this structure can predispose to small intestinal bacterial overgrowth,steatorrhoea and deconjugation of bile salts<sup>2</sup>. However, removing the ileocaecocolic valve minimises the recurrence of megacolon.  
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Although sub-total colectomy is an effective way of correcting megacolon, removal of majority of the colon does have adverse effects on the animal. For example, the colon normally functions to absorb water. This is achieved by the creation of an osmotic gradient by active sodium absorbtion. Additionally, extracellular potassium is lost and bicarbonate ions are exchanged for chloride ions in the colon. It could therefore be implied that sub-total colectomy disrupts water and electrolyte homeostasis. However, cats undergoing sub-total colectomy have been found to show no clinical evidence of abnormal bowel function<sup>6</sup>.
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are secreted in exchange for chloride
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ions, and potassium is lost from extracellular
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fluid; in addition, mucus and cells are shed into the colon.
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Questions remain about water and electrolyte homeostasis, and
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absorption of specific nutrients such as vitamin K following subtotal
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colectomy. Enteric function following subtotal colectomy has been
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evaluated in both normal and clinically affected cats and no significant
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clinical or subclinical evidence of abnormal bowel function
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was found (Gregory and others 1990). Histology of the small
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intestinal wall following subtotal colectomy showed increases in
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villus height, enterocyte height and density, with an increased
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mucosal absorptive area. Serum cobalamin and faecal sodium
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levels were higher in cats treated surgically, and faecal potassium
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was low; however, the significance of these findings is unknown.
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Tenesmus and loose faeces are often seen immediately postsurgery,
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with faeces gradually progressing to soft but formed by
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about three months; resection of the ileocaecocolic valve is, however,
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associated with persistence of looser stools.
   
The issue of exactly how much of the colon to remove will remain
 
The issue of exactly how much of the colon to remove will remain
 
controversial until more information is published regarding longterm
 
controversial until more information is published regarding longterm
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and partial colectomy provide little or no long-term improvement
 
and partial colectomy provide little or no long-term improvement
 
and are not recommended.
 
and are not recommended.
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Although sub-total colectomy is an effective way of correcting megacolon, removal of majority of the colon has the potential to cause metabolic effects in the animal. For example, the colon normally functions to absorb water. This is achieved by the creation of an osmotic gradient by active sodium absorbtion. Additionally, extracellular potassium is lost and bicarbonate ions are exchanged for chloride ions in the colon. It could therefore be implied that sub-total colectomy disrupts water and electrolyte homeostasis, but paradoxically cats undergoing sub-total colectomy have been found to show no clinical evidence of abnormal bowel function<sup>6</sup>. However, other, non-clinical changes were found: small intestinal enterocytes and villi were increased in height, the absorptive area of the small intestinal muscosa was increased, serum cobalamin and faecal sodium were increased and faecal potassium was low. The significance of these results is unknown.
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After surgery faeces are loose and defaecation is associated with tenesemus, but faecal consistency improved over the following months. Complications associated with the surgery itself are rare and tend to related to the anastomotic procedure<sup>2</sup>. For example, the abdomen may become contaminated during surgery, leading to peritonitis, or the anastomosis site may break down. 
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Complications associated with subtotal colectomy
 
Complications associated with subtotal colectomy
 
Operative complications are uncommon. Where reported, complications generally relate to the anastomotic procedure; for example,
 
Operative complications are uncommon. Where reported, complications generally relate to the anastomotic procedure; for example,
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