Pathological changes depend on the direction of penetration; this is usually in an anterior-ventral direction. Pyogenic bacteria escape from the [[The Reticulum - Anatomy & Physiology|reticulum]], causing localised [[Peritonitis|peritonitis]] and local fibrinous adhesions. | Pathological changes depend on the direction of penetration; this is usually in an anterior-ventral direction. Pyogenic bacteria escape from the [[The Reticulum - Anatomy & Physiology|reticulum]], causing localised [[Peritonitis|peritonitis]] and local fibrinous adhesions. |