Changes

Demonstration of antibodies in serum, aqueous humour or CSF is indicative of exposure to ''T. gondii'', but does not necessarily show active infection. This could be overcome by testing for ''T. gondii'' antigen or immune complexes, but these methods are currently only available to researchers. Several techniques are commercially available for detection of antibody, including ELISA,

Demonstration of antibodies in serum, aqueous humour or CSF is indicative of exposure to ''T. gondii'', but does not necessarily show active infection. This could be overcome by testing for ''T. gondii'' antigen or immune complexes, but these methods are currently only available to researchers. Several techniques are commercially available for detection of antibody, including ELISA,

immunofluorescent antibody testing, western blot immunoassay, Sabin-Feldmann dye test, and agglutination tests. Although these tests are theoretically able to detect all classes of immunoglobulin against ''Toxoplasma gondii'' in many species, it seems that feline serum positive for IgM only often reads as a false negative^{5, 6}

immunofluorescent antibody testing, western blot immunoassay, Sabin-Feldmann dye test, and agglutination tests. Although these tests are theoretically able to detect all classes of immunoglobulin against ''Toxoplasma gondii'' in many species, it seems that feline serum positive for IgM only often reads as a false negative^{5, 6} and so careful interpretation is necessary, particularly since the IgM antibody class appears to correlate more closely to clinical disease than IgG⁷.

 

T gondii-specific IgG can be detected by ELISA in

T gondii-specific IgG can be detected by ELISA in

serum in the majority of healthy, experimentally inoculated

serum in the majority of healthy, experimentally inoculated