Changes

Lymphatic nodules are present in the mucosal surfaces and are more readily defined than other more diffuse lymphoid tissue of the MALT but are still not encapsulated. They exist with small primary nodule or generally as secondary nodules containing germinal centres. The nodules are generally found in the [[Tonsils - Anatomy & Physiology|tonsils]], [[Peyer's Patches - Anatomy & Physiology|Peyer’s patches]] and [[Appendix - Anatomy & Physiology|appendix]] and become enlarged when responding to an antigen.</p>

Lymphatic nodules are present in the mucosal surfaces and are more readily defined than other more diffuse lymphoid tissue of the MALT but are still not encapsulated. They exist with small primary nodule or generally as secondary nodules containing germinal centres. The nodules are generally found in the [[Tonsils - Anatomy & Physiology|tonsils]], [[Peyer's Patches - Anatomy & Physiology|Peyer’s patches]] and [[Appendix - Anatomy & Physiology|appendix]] and become enlarged when responding to an antigen.</p>

==Functions==

==Functions==

<p>As with other [[Secondary Lymphoid Tissue - Anatomy & Physiology|secondary lymphoid tissue]] the role of the MALT is to mount an immune response to pathogenic antigens. Cells in the MALT sample antigens at the mucosal surface and then migrate to regional [[Lymph Nodes - Anatomy & Physiology|lymph nodes]] where they divide and differentiate before returning to the mucosal surface as effector cells.</p>

<p>As with other [[:Category:Secondary Lymphoid Tissue|secondary lymphoid tissue]] the role of the MALT is to mount an immune response to pathogenic antigens. Cells in the MALT sample antigens at the mucosal surface and then migrate to regional [[Lymph Nodes - Anatomy & Physiology|lymph nodes]] where they divide and differentiate before returning to the mucosal surface as effector cells.</p>

<p>In the GALT TGF-β is produced and this causes the [[Lymphocytes#B cells|B cells]] to produce [[Immunoglobulin A|IgA]].</p>

<p>In the GALT TGF-β is produced and this causes the [[Lymphocytes#B cells|B cells]] to produce [[Immunoglobulin A|IgA]].</p>