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| ===Transmission to Sheep=== | | ===Transmission to Sheep=== |
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− | Infected cats shed oocysts continuously between days 3 and 14 post-infection. During this time, tens of millions of oocysts may be shed. The main sources of feline toxoplasma infection are chronically infected birds and rodents. Rodents are particularly important since they can pass ''T. gondii'' infection to their offspring without causing clinical disease. This means that a location may develop a reservoir of ''T. gondii'' tissue cysts with the potential to cause feline infection and massive oocyst excretion. In turn, environments may easily become contaminated with a high oocyst burdedn/ | + | Infected cats shed oocysts continuously between days 3 and 14 post-infection. During this time, hundreds of millions of oocysts may be shed. The main sources of feline toxoplasma infection are chronically infected birds and rodents. Rodents are particularly important since they can pass ''T. gondii'' infection to their offspring without causing clinical disease. This means that a location may develop a reservoir of ''T. gondii'' tissue cysts with the potential to cause feline infection and massive oocyst excretion. In turn, environments may easily become contaminated with a high oocyst burden when a cat is introduced. |
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− | | + | Sheep are often kept in an environment that is significantly contaminated with oocysts, and infection follows ingestion of infected food, primarily contaminated pasture. Fields treated with manure or bedding from buildings to which cats have access result in high levels of ovine toxoplasmosis, and insecure storage of supplementary feeds also poses a risk. |
− | The available epidemiological and experimental
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− | evidence suggests that, in the UK, sheep are
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− | frequently maintained in an environment significantly
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− | contaminated with oocysts and that infection follows | |
− | ingestion of infected food17"8. Perhaps the most | |
− | common source of infection is contaminated pasture.
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− | Certainly, fields treated with manure and bedding
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− | from farm buildings where cats live can cause | |
− | infection'9. Careless storage of farm feeds may also
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− | pose a risk20. Fifty grams of infected cat faeces may
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− | contain as many as 10 million oocysts9. If in a
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− | hypothetical situation this was evenly dispersed
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− | throughout 10 tonnes of concentrated animal feed
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− | then each kilogram could contain between five and
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− | 25 sheep-infective doses21. The extent of environmental
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− | contamination with T. gondii oocysts is thus
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− | related to the distribution and behaviour of cats.
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− | Measures to reduce environmental contamination
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− | by oocysts should be aimed at reducing the number
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− | of cats capable of shedding oocysts. This would include
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− | attempts to limit their breeding. If male cats are
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− | caught, neutered and returned to their colonies the
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− | stability ofthe colony is maintained; fertile male cats
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− | do not challenge the neutered males12 and breeding
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− | is controlled. Thus the maintenance ofa small healthy
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− | population of mature cats will reduce oocyst excretion
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− | as well as help to control rodents. Sheep feed should be
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− | kept covered at all times to prevent its contamination
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− | by cat faeces.
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| ==Signalment== | | ==Signalment== |