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| Both the innate and adaptive immune systems use receptors to recognise foreign organisms. The innate immune system uses pattern recognition receptors which acts as an early warning system. The adaptive immune response is highly specific for each organism, as B and T cells have specialist surface immunoglobulin receptors which detect specific antigens on foreign pathogens. | | Both the innate and adaptive immune systems use receptors to recognise foreign organisms. The innate immune system uses pattern recognition receptors which acts as an early warning system. The adaptive immune response is highly specific for each organism, as B and T cells have specialist surface immunoglobulin receptors which detect specific antigens on foreign pathogens. |
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− | =Introduction=
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| The Innate immune system is the body's first barrier of defence to infection. It relies on an older, more generic, and faster acting set of tools than the [[Adaptive Immune System - WikiBlood|adaptive]] system. While the adaptive system is essential for a specific response to infection, it is ultimately the innate system that conquers foreign attackers through means of phagocytosis. | | The Innate immune system is the body's first barrier of defence to infection. It relies on an older, more generic, and faster acting set of tools than the [[Adaptive Immune System - WikiBlood|adaptive]] system. While the adaptive system is essential for a specific response to infection, it is ultimately the innate system that conquers foreign attackers through means of phagocytosis. |
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− | * Non-specific protective mechanisms include such innate factors as:
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− | ** '''Physical barriers'''
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− | *** Skin
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− | *** Ciliated mucous membranes
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− | *** Commensal organisms
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− | ** '''Humoral factors'''
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− | *** Lysozyme
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− | *** [[Complement|Complement]]
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− | *** Interferons
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− | ** '''Cellular mechanisms'''
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− | *** Phagocytosis
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− | ** Factors which regulate '''species specificity'''
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− | *** Membrane receptors for pathogens
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− | *** Nutritional requirements
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− | *** Temperature
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− | *** pH
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− | * Mechanisms of innate immunity are always present and generally unchanging
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− | * Adaptive immunity is acquired only on contact with the infectious agent (antigen) and therefore does not function before first contact with the antigen
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− | =Actions of the Innate Immune System=
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− | ==[[Recognition of Microorganisms]]==
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− | ==[[Phagocytosis]]==
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− | =Tools of Innate Immunity=
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− | ==[[Innate Immunity Barriers]]==
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− | ==[[Humoral Factors of Innate Immune System]]==
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− | ==[[Innate Immunity Cellular Responses]]==
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− | =[[Innate Immunity to Viruses]]=
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− | =[[Innate Immunity to Bacteria]]=
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− | =[[Interplay of Innate and Adaptive Immunity - WikiBlood|Interplay of Innate and Adaptive Immunity]]= | + | =[[Innate Immune System - Introduction]]= |
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− | =[[Innate Immunity Flashcards|Innate Immunity Flashcards]]=
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− | =Links=
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− | '''Websites'''
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− | *http://www.cellsalive.com
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− | =References=
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| [[Category:Immunology]] | | [[Category:Immunology]] |