Changes

==Alloantibodies==

==Alloantibodies==

Unlike [[Blood Groups - Cat|cats]] dogs do not have natural alloantibodies against other blood groups unless a transfusion has been performed.

Unlike [[Blood Groups - Cat|cats]] dogs do not have natural alloantibodies against other blood groups unless a transfusion has been performed.

There is no major risk for the first transfusion and consequently unlike the cat compatibility tests are not required.

There is no major risk for the first transfusion and consequently unlike the cat compatibility tests are not required for the dogs first transfusion.

Following the first transfusion of blood, alloantibodies form within 5-7 days.  If a second tranfusion is required 5 days later than the original transfusion compatibility tests are required.

Following the first transfusion of blood, alloantibodies form within 5-7 days and if a second tranfusion is required 5 days later than the original transfusion compatibility tests are required.

DEA 1.1 and DEA 1.2 are the most antigenic and hence ideally a donor would be DEA 1.1 and DEA 1.2 negative. Dogs are either DEA 1.1 positive or DEA 1.2 positive or negative fot both DEA 1.1 and 1.2.

Dogs are either DEA 1.1 positive or DEA 1.2 positive or negative for both DEA 1.1 and 1.2.

DEA 1.1 and DEA 1.2 are the most antigenic and hence ideally a donor would be DEA 1.1 and DEA 1.2 negative.  

Transfusion reactions can occur when DEA 1.1 and 1.2 negative dogs recieve DEA 1.1 or 1.2 positive blood.

Transfusion reactions can occur when DEA 1.1 and 1.2 negative dogs recieve DEA 1.1 or 1.2 positive blood.

 

[[Neonatal Isoerythrolysis|Neonatal isoerythrolysis]] can also occur in dogs. This happens when a DEA 1 negative female which has previosuly been sensitised to DEA 1 positive blood is mated to a DEA 1.1 positive male.

[[Category:Transfusion Medicine]]

[[Category:Transfusion Medicine]]