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Adaptive Immunity to Bacteria (view source)
Revision as of 13:23, 16 August 2010
, 13:23, 16 August 2010Created page with "*The adaptive and innate responses work together to destroy bacteria *The adaptive response ensures the innate response is carr..."
*The adaptive and [[Innate Immune System|innate responses]] work together to destroy bacteria
*The adaptive response ensures the [[Innate Immune System|innate response]] is carried out efficiently
'''Humoral'''
*[[Complement|Complement]] activation of the classical pathway
**Production of [[Immunoglobulin M|IgM]] and [[Immunoglobulin G|IgG]] makes the complement system more efficient
'''Cell-Mediated'''
*Help for macrophages
**[[Immunoglobulin G|IgG]] production (T-helper type II cells and [[Lymphocytes#B Cells|B cells]]) which improves phagocytosis by opsonisation
**Infected [[Macrophages|macrophages]] are rescued by T-helper type I cells when phagocytosis and digestion mechanisms fail to eliminate the pathogen
'''Extracellular Infection'''
*Complement and phagocytosis
*[[Lymphocytes#B Cells|B cell]] and T helper type II cell stimulation
*Production of [[Immunoglobulin M|IgM]] which activates the classical cascade
*Class switching of [[Immunoglobulin M|IgM]] to [[Immunoglobulin G|IgG]] which is a good opsonin and targets bacterial Fcγ receptor expressed by [[Macrophages|macrophages]] and [[Neutrophils|neutrophils]]
'''Vesicular Infection'''
*The infected [[Macrophages|macrophage]] secretes IL-12
*IL-12 stimulates T-helper type I cells which release IFN-γ
*IFN-γ triggers the [[Macrophages|macrophages]] to kill the pathogens inside
[[Category:To Do - Blood]]
*The adaptive response ensures the [[Innate Immune System|innate response]] is carried out efficiently
'''Humoral'''
*[[Complement|Complement]] activation of the classical pathway
**Production of [[Immunoglobulin M|IgM]] and [[Immunoglobulin G|IgG]] makes the complement system more efficient
'''Cell-Mediated'''
*Help for macrophages
**[[Immunoglobulin G|IgG]] production (T-helper type II cells and [[Lymphocytes#B Cells|B cells]]) which improves phagocytosis by opsonisation
**Infected [[Macrophages|macrophages]] are rescued by T-helper type I cells when phagocytosis and digestion mechanisms fail to eliminate the pathogen
'''Extracellular Infection'''
*Complement and phagocytosis
*[[Lymphocytes#B Cells|B cell]] and T helper type II cell stimulation
*Production of [[Immunoglobulin M|IgM]] which activates the classical cascade
*Class switching of [[Immunoglobulin M|IgM]] to [[Immunoglobulin G|IgG]] which is a good opsonin and targets bacterial Fcγ receptor expressed by [[Macrophages|macrophages]] and [[Neutrophils|neutrophils]]
'''Vesicular Infection'''
*The infected [[Macrophages|macrophage]] secretes IL-12
*IL-12 stimulates T-helper type I cells which release IFN-γ
*IFN-γ triggers the [[Macrophages|macrophages]] to kill the pathogens inside
[[Category:To Do - Blood]]