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====Primary Thrombocytopenic Disease====
==Description==
Platelets (or thrombocytes) are responsible for primary haemostasis, the formation of a temporary platelet plug that initially seals any breach to a blood vessel wall. Bleeding disorders may occur if platelets are deficient ('''thrombocytopenia''') or if the platelets are unable to function adequately ('''thrombocytopathia'''). Thrombocytopenia may be a '''primary disease''' due to disease of the bone marrow that reduces the production of platelets or it may occur '''secondary''' to another insult.
===Primary Thrombocytopenic Disease===
The aetiology of primary thrombocytopenic disease is often uncertain and it is therefore also known as '''idiopathic''' thrombocytopenia. Some cases of primary thrombocytopenia may occur due to autoimmune responses directed at platelets and, although the [[Bone Marrow - Anatomy & Physiology|bone marrow]] may contain adequate normal megakaryocytes, this disease results in a reduced peripheral blood thrombocyte count. [[Immune Mediated Thrombocytopenia|Immune-mediated thrombocytopenia]] occurs most commonly in young animals.
===Secondary Thrombocytopenic Disease===
Secondary thrombocyopaenic disease is fairly common in adult domestic animals and it may be associated with diseases that depress the production of platelets or increase their consumption.
* Associated with diseases which cause [[Bone Marrow - Anatomy & Physiology|bone marrow]] depression.
* Associated with diseases which cause [[Bone Marrow - Anatomy & Physiology|bone marrow]] depression.
* The [[Bone Marrow - Anatomy & Physiology|bone marrow]] is depleted or devoid of megakaryocytes, and there is a nil or markedly reduced peripheral blood thrombocyte count.
* The [[Bone Marrow - Anatomy & Physiology|bone marrow]] is depleted or devoid of megakaryocytes, and there is a nil or markedly reduced peripheral blood thrombocyte count.
====Thrombocytopathia====
====Thrombocytopathia====
{{unfinished}}
Von Willebrands, Angiostrongylus, colloids, granule disease.
* A rare inherited condition.
* A rare inherited condition.
* Recorded in the dog.
* Recorded in the dog.
[[Category:Haemorrhagic Diseases]]
[[Category:Haemorrhagic Diseases]]
[[Category:To Do - Blood]]
[[Category:To Do - James]]