Changes

====Other Tests====

====Other Tests====

An '''in-saline agglutination''' test may be used to diagnose cases of IMHA that involve aut-agglutination.  A drop of whole blood is mixed with a drop of plain saline on a glass slide and agitated for 30-60 seconds.  A positive result is recorded if evident aggregates form but the slide should be evaluated under a microscope as rouleaux formation may result in a similar gross appearance.  

An '''in-saline agglutination''' test may be used to diagnose cases of IMHA that involve auto-agglutination.  A drop of whole blood is mixed with a drop of plain saline on a glass slide and agitated for 30-60 seconds.  A positive result is recorded if evident aggregates form but the slide should be evaluated under a microscope as rouleaux formation may result in a similar gross appearance.  

A '''Coomb's test''' can be used to diagnose cases of IMHA that are caused by incomplete antibodies.  The red blood cells from a patient are mixed with Coomb's antiserum (IgG antiobies directed against IgG) and, in cases where the patient has IMHA with antibodies attached to the surface of the erythrocytes, the antiserum will result in the formation of aggregates of cells.  The titre of the test should be evaluated as weakly positive results may occur with other diseases.

A '''Coomb's test''' can be used to diagnose cases of IMHA that are caused by incomplete antibodies.  The red blood cells from a patient are mixed with Coomb's antiserum (IgG antiobies directed against IgG) and, in cases where the patient has IMHA with antibodies attached to the surface of the erythrocytes, the antiserum will result in the formation of aggregates of cells.  The titre of the test should be evaluated as weakly positive results may occur with other diseases.