Changes

As thrombi form in the vasculature tissues will become hypoxic leading to multisystemic organ failure in severe cases.   

As thrombi form in the vasculature tissues will become hypoxic leading to multisystemic organ failure in severe cases.   

As [[Thrombocytes|platelets]] are used up in the thrombi a [[Platelet Abnormalities#Thrombocytopaenia]] thrombocytopaenia occurs, leading to a paradoxical haemorrhage and the patient starts to bleed.  This is the mechanism by which most viral haemorrahgic diseases cause their clinical signs.

As [[Thrombocytes|platelets]] are used up in the thrombi a [[Platelet Abnormalities#Thrombocytopaenia|thrombocytopaenia]] occurs, leading to a paradoxical haemorrhage and the patient starts to bleed.  This is the mechanism by which most viral haemorrahgic diseases cause their clinical signs.

==Diagnosis==

==Diagnosis==