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Disseminated Intravascular Coagulation (view source)
Revision as of 09:38, 18 August 2010
, 09:38, 18 August 2010→Prognosis
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* Disseminated intravacular coagulation is a widespread intravascular coagulation of the microcirculation.
−* The capillaries are principally affected.
−* There are various causes.
−** Mismatched blood transfusion
−** Acute haemolytic crises
−** Extensive burns and trauma
−** Infectious and post-infectious immunologic reactions.
* Haemorrhagic diathesis may develop.+
−** Is a result of rapid consumption and depletion of fibrinogen, platelets and clotting factors
−* The fibrinolytic system is also highly stimulated to prevent what little clotting activity that remains.
DIC has a poor prognosis with a high mortality rate.
DIC has a poor prognosis with a high mortality rate.
−* There is widespread occlusion of the microcirculation with small white thrombi.
* There is widespread occlusion of the microcirculation with small white thrombi.
** May cause [[Shock|shock]], acute respiratory distress, heart failure or renal failure.
** May cause [[Shock|shock]], acute respiratory distress, heart failure or renal failure.
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