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Type IV Hypersensitivity
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==Introduction==
==Introduction==
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[[Image:Sensitisation phase Type IV Hypersensitivity.jpg|right|thumb|150px|Sensitisation phase: Type
VI
hypersensitivity-Brian Catchpole RVC 2008]]
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[[Image:Sensitisation phase Type IV Hypersensitivity.jpg|right|thumb|150px|Sensitisation phase: Type
IV
hypersensitivity-Brian Catchpole RVC 2008]]
−
[[Image:Delayed type hypersensitivity.jpg|right|thumb|150px|Type
VI
hypersensitivity-Brian Catchpole RVC 2008]]
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[[Image:Delayed type hypersensitivity.jpg|right|thumb|150px|Type
IV
hypersensitivity-Brian Catchpole RVC 2008]]
Cell mediated hypersensitivity:
Cell mediated hypersensitivity:
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* Presently in the UK the animal is culled if it has a positive skin reaction.
* Presently in the UK the animal is culled if it has a positive skin reaction.
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==From Pathology==
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*Delayed hypersensitivity
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*Haptens bind to carrier proteins (mainly epidermal)
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*Mediated by sensitised [[T cell differentiation|T-cells]] -> release cytokines +/- recruit lymphocytes
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*Used in diagnosis of tuberculosis, histoplasmosis and coccidiomycosis
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*Perivascular mononuclear cell accumulation
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<br><br>
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{{Jim Bee 2007}}
[[Category:Hypersensitivity]]
[[Category:Hypersensitivity]]
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[[Category:Image Review]]
Sineadvet
1
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