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*Heart has a ''globoid'' shape
*Heart has a ''globoid'' shape
*Ventricular wall measurements:
*Ventricular wall measurements:
**Interventricular septum; 12mm
**Interventricular septum; 12mm[[Image:hypertrophic cardiomyopathy 2.jpg|right|thumb|125px|<small><center>'''Hypertrophic cardiomyopathy (cat)'''. Courtesy of T. Scase</center></small>]]
[[Image:hypertrophic cardiomyopathy 2.jpg|right|thumb|125px|<small><center>'''Hypertrophic cardiomyopathy (cat)'''. Courtesy of T. Scase</center></small>]]**Right ventricular wall; 3mm
**Right ventricular wall; 3mm
**Left ventricular wall; 10mm
**Left ventricular wall; 10mm
*Pericardium is fatty, shiny and intact
*Pericardium is fatty, shiny and intact
The other body systems were examined.<br>
The other body systems were examined.<br>
No further abnormalities were found.
No further abnormalities were found.
<br><br><br>
==Histopathology==
==Histopathology==
[[Image:Case pic 3.jpg|left|thumb|125px|<small><center>'''Histology; hypertrophic cardiomyopathy'''. Courtesy of K. Hughes</center></small>]]
[[Image:Case pic 3.jpg|right|thumb|125px|<small><center>'''Histology'''. Courtesy of K. Hughes</center></small>]]
Samples were taken for histological examination (Stained with H and E):
Samples were taken for histological examination (Stained with H and E):
*The cardiac myocytes are multifocally widely spaced and infiltrated by streams of spindle shaped cells (fibroblasts).
*The cardiac myocytes are multifocally widely spaced and infiltrated by streams of spindle shaped cells (fibroblasts).
[[Image:Case pic 4.jpg|right|thumb|125px|<small><center>'''Massons Trichrome'''. Courtesy of K. Hughes</center></small>]]
Some sections were stained with Massons Trichrome:
Some sections were stained with Massons Trichrome:
*This confirmed the presence of large, multifocal areas of fibrosis within the inner third of the myocardium and extending to the endocardial surface.
* This confirmed the presence of large, multifocal areas of fibrosis within the inner third of the myocardium and extending to the endocardial surface.
*Multifocally the fibrosis surrounds individual atrophied myocytes.
* Multifocally the fibrosis surrounds individual atrophied myocytes.
*There is mural thickening (smooth muscle hypertrophy) of the intramyocardial arteries.
* There is mural thickening (smooth muscle hypertrophy) of the intramyocardial arteries.
<br><br>
==Diagnosis==
The gross post mortem findings indicated a '''severe hypertrophic cardiomyopathy''' which was confirmed on histology.
The fibrosis seen is a common sequale to this type of disease. The hypertrophy in the ventricular wall limits blood supply to the inner third of myocardium. Reduced perfusion stimulates replacement of degenerate myocytes with fibrous tissue, extending into the endocardium.
[[Category:Lost]]