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The disease can then invade a specific organ system resulting in associated clinical signs:
 
The disease can then invade a specific organ system resulting in associated clinical signs:
   −
* Opthalmic
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'''Opthalmic''': The initial signs are blephrospasm, increased lacrimation, photophobia and corneal oedema, with progression to retinal detachment, synechia formation, and cataracts. Chronic leptospirosis causes recurrent uvietis.
Chronic leptospirosis causes recurrent uvietis
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* Abortion
     −
* Renal
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'''Reproductive''': Leptospirosis can cause abortion, still birth or neonatal disease depending on the serovar and the stage of gestation when infected. Abortions are most frequently late term.
   −
* Hepatic
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'''Renal''':
 +
 
 +
'''Hepatic''':
    
Horses with subclinical infections or those in the carrier state are asymptomatic.  
 
Horses with subclinical infections or those in the carrier state are asymptomatic.  
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