Changes

===Clinical Signs===

===Clinical Signs===

As described above, the onset of clinical signs in anticoagulant rodenticide toxicosis is delayed for up to five days while previously formed clotting factors reach the end of their life-spans and function facts become depleted.

As described above, the onset of clinical signs in anticoagulant rodenticide toxicosis is delayed for up to five days while vitamin K dependent factors become depleted, due to the gradual degradation of functional factors already in the circulation. When signs occur, they are related to defective haemostasis and unchecked haemorrhage. Visible signs can include external haematomas, bruising, excessive bleeding from venupuncture sites, epistaxis, haematemesis, haemtotochezia, melaena or haematuria Symptoms may be non-specific

is delayed for several days post-exposure while the plasma

concentrations of the vitamin K-dependent clotting

factors become depleted. Symptoms may be non-specific

if there is internal bleeding, and might include depression,

if there is internal bleeding, and might include depression,

weakness, pallor, dyspnoea, abdominal swelling,

weakness, pallor, dyspnoea, abdominal swelling,

or even sudden death. Other possible signs include

or even sudden death.  

and/or lameness.

and/or lameness.