Background srain, longelivity. Their melanism is manifested by their coat colour. melanin pigment in heart valves, splenic capsule and meninges.
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Gold standard background strain for GEM's, genome of this strain has been fully sequenced. B6 mice were initially bred for their longevity. Their melanism is manifested by their coat colour. melanin pigment in heart valves, splenic capsule and meninges.
'''Spontaneous diseases:'''
'''Spontaneous diseases:'''
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Hydrocephalus, hippocampal neurodegeneration, microphtalmia, anophtalmia, age realted cochlear degeneration (hearing loss), malocclusion and pulmonary proteinosis.