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Laboratory mice strain information (view source)
Revision as of 13:41, 25 August 2010
, 13:41, 25 August 2010no edit summary
==BALB/c mice:==
==BALB/c mice:==
Albinos. Mature males are rather pugilistic.
'''Spontaneous diseases:'''
'''Spontaneous diseases:'''
Dystrophic epicardial mineralisation of the right ventricular free wall, myocardial degeneration, auricular thrombosis, corneal opacities, hypocallosity (corpus callosus hypoplasia or even aplasia, age-related hearing loss.
Dystrophic epicardial mineralisation of the right ventricular free wall, myocardial degeneration, auricular thrombosis, corneal opacities, hypocallosity (corpus callosus hypoplasia or even aplasia), age-related hearing loss.
BALB mice are markedly ressistant to amyloidosis
BALB mice are markedly ressistant to amyloidosis.
'''Common neoplasms:'''
'''Common neoplasms:'''
==C3H/He mice:==
==C3H/He mice:==
Agouti (brown) mice that are blind due to ''rd1'' mutation in the ''Pdeb'' gene.
'''Spontaneous diseases:'''
'''Spontaneous diseases:'''
Focal myocardial and skeletal mineralisation and myocardial degeneration, alopecia areata (females more than males).
'''Common neoplasms:'''
'''Common neoplasms:'''
They are more susceptible to exogenous murine mammary tumours virus (MMTV)-induced mammary tumours and develop a relatively high incidence of mammary neoplasia later in life due to endogenous MMTV.
Other common tumours include hepatocellular tumours.
==129 mice:==
==129 mice:==
Represent the most frequent source of embryonic stem cells (ES cells). The 129 mouse is not a single strain, and in fact the "129" is represented by 16 recognised strains and substrains.
'''Spontaneous diseases:'''
'''Spontaneous diseases:'''