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===Improving Cutaneous Barrier Function===
 
===Improving Cutaneous Barrier Function===
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In normal animals, the skin has an important barrier function. The integrity of the epithelium may be impaired in atopic animals, facilitating further exposure to allergens. Finding ways to help improve the barrier function of the epidermis can contribute towards the effective management of atopy. Food trials are often used during the course of a work-up for atopic dermatitis to eliminate food allergy as a cause of pruritus. Many atopic animals non-specifically improve during food trials on prescription hypoallergenic diets, which may be attributable to several of their components. The inclusion of zinc and long-chain omega essential fatty acids is thought to reduce inflammation, and substances such as inositol, choline, histidine, pantothenate and nicotinamide may help improve epidermal lipid barrier<sup>4</sup>. The use of topical shampoos and emollients can also be beneficial. As well as physically removing allergens from the skin and coat, moisturising shampoos can hydrate the skin and improve the lipid barrier. Colloidal oatmeal may also have a direct antipruritic action<sup>4</sup>. Anti-microbial or anti-scaling shampoos, and ear cleaners can prove useful in certain cases depending on presentation. The effects of essential fatty acids in atopic dermatitis have been subjected to numerous clinical trials. EFA supplementation alters incorporation into cell membranes, which may reduce production of pro-inflammatory leukotrienes and prostaglandins<sup>4</sup>. The cutaneous lipid barrier may also be improved. However, there is some conflicting informtation, and high levels of supplementation may be neccessary to give beneficial effects.
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In normal animals, the skin has an important barrier function. The integrity of the epithelium may be impaired in atopic animals, facilitating further exposure to allergens. Finding ways to help improve the barrier function of the epidermis can contribute towards the effective management of atopy. Food trials are often used during the course of a work-up for atopic dermatitis to eliminate food allergy as a cause of pruritus. Many atopic animals non-specifically improve during food trials on prescription hypoallergenic diets, which may be attributable to several of their components. The inclusion of zinc and long-chain omega essential fatty acids is thought to reduce inflammation, and substances such as inositol, choline, histidine, pantothenate and nicotinamide may help improve epidermal lipid barrier<sup>3</sup>. The use of topical shampoos and emollients can also be beneficial. As well as physically removing allergens from the skin and coat, moisturising shampoos can hydrate the skin and improve the lipid barrier. Colloidal oatmeal may also have a direct antipruritic action<sup>3</sup>. Anti-microbial or anti-scaling shampoos, and ear cleaners can prove useful in certain cases depending on presentation. The effects of essential fatty acids in atopic dermatitis have been subjected to numerous clinical trials. EFA supplementation alters incorporation into cell membranes, which may reduce production of pro-inflammatory leukotrienes and prostaglandins<sup>3</sup>. The cutaneous lipid barrier may also be improved. However, there is some conflicting informtation, and high levels of supplementation may be neccessary to give beneficial effects.
    
===Allergen Specific Therapy===
 
===Allergen Specific Therapy===
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