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* Like [[Bloat|bloat]], rumenal acidosis is associated with mismanagement of feeding and involves cessation or depression of [[Rumination - Anatomy & Physiology|rumenal movements]] with development of a degree of tympany.
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==Description==
* More common in cattle and goats than in sheep due to differences in diet.
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===Clinical===
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==Signalment==
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==Diagnosis==
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===Clinical Signs===
    
* Animals display signs of abdominal discomfort, but usually recover if treated.
 
* Animals display signs of abdominal discomfort, but usually recover if treated.
 
* Acute disease can result in death if acidosis is severe.
 
* Acute disease can result in death if acidosis is severe.
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===Pathogenesis===
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* Occurs following feeding of highly fermentable material, usually carbohydrate, in the form of concentrate or cereal
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** e.g. in barley beef feeding systems.   
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* An overgrowth of Gram positive bacteria results, breaking carbohydrate down very quickly.
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** Increased [[Volatile Fatty Acids - Anatomy & Physioogy|volatile fatty acid]] production decreases the [[The Rumen - Anatomy & Physiology|rumen]] pH to about 5. 
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*** [[The Rumen - Anatomy & Physiology|Rumen]] epithelium is damaged- ruminitis.
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*** Osmotic effects of [[The Rumen - Anatomy & Physiology|rumen]] contents produce severe dehydration.
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*** Death may ensue when the [[The Rumen - Anatomy & Physiology|rumen]] pH drops to 4.5 or below.
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* Normal flora may invade the damaged wall of [[The Rumen - Anatomy & Physiology|rumen]] e.g. Fusiformis necrophorum.
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** Results in areas with mushy necrotic papillae.
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** Especially on pillars and ventral parts of [[The Rumen - Anatomy & Physiology|rumen]].
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* Excess gas production may occur
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** Concentrate does not contain soluble proteins, therefore foam does not develop.
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** Only mild to moderate free gas bloat is likely- much of the rumenal distension which occurs with rumenal acidosis is due to fluid sequestration in the [[The Rumen - Anatomy & Physiology|rumen]].
      
===Pathology===
 
===Pathology===
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====Gross====
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==Treatment==
 
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* Gross PM findings may be non-specific.
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* Ruminal stasis/bloat leads to rumen distension
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* [[The Rumen - Anatomy & Physiology|Rumen]] contents are porridge-like.
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* Rumenitis may be present
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** Normal flora invading wall of rumen may enter blood as thromboemboli and travel in the portal flow to [[Liver - Anatomy & Physiology|liver]]
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** Focal abscesses are produced, which heal with sunken star-shaped scars.
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* Overgrowth of Clostridia may cause endotoxic shock with widespread petechial haemorrhages.
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====Histological====  
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==Prognosis==
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* Microvesicles may be present  in the epithelium of the [[The Rumen - Anatomy & Physiology|rumen]] papillae.
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==Links==
** Contain mainly [[Neutrophils|neutrophils]]
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* May be focal erosions/ulceration.
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===Sequelae===
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==References==
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* Scarring- necrotised papillae are replaced by smooth epithelium closely adherent to sub mucosa.
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[[Category:Forestomach_-_Nutritional_Pathology]][[Category:Cattle]][[Category:Sheep]][[Category:Goat]][[Category:To_Do_-_Lizzie]]
* Has economic significance since many barley beef livers are condemned at meat inspection.
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* More persistent organisms can invade [[The Rumen - Anatomy & Physiology|rumen]] wall producing chronic infection.
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** These are often fungi, e.g. Mucor (see [[Mucormycosis|Mucormycosis]]).[[Category:Forestomach_-_Nutritional_Pathology]][[Category:Cattle]][[Category:Sheep]][[Category:Goat]][[Category:To_Do_-_Lizzie]]
 
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