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Also known as '''Sweet Itch'''
 
Also known as '''Sweet Itch'''
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*Usually involves [[Skin Immunologic - Pathology#Type I reactions|Type I reaction]] and [[Skin Immunologic - Pathology#Type IV reactions|Type IV reaction]]  due to salivary antigens of ''Culicoides'' sp.
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==Description==
*May be seasonally recurring or continuous depending on climate
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Culicoides hypersensitivity, commonly referred to as 'Sweet itch' is an intensely pruritic dermatitis of horses caused by a hypersensitivity reaction to the saliva of biting ''Culicoides'' midges. The condition may be seasonally recurring or continuous depending on the climate
*Grossly:
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==Pathogenesis==
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The condition is thought to occur due to both immediate (Type 1) and delayed (Type 4) hypersensitivity reactions to Culicoides salivary proteins. These proteins are injected during feeding and susceptible animals respond to them by producing IgE antibodies.
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*Grossly:s
 
**Papules, crusts, alopecia, excoriations, lichenification
 
**Papules, crusts, alopecia, excoriations, lichenification
 
*Microscopically:
 
*Microscopically:
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