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| | + | ==Description== |
| | + | Leptospirosis is an important zoonosis, affecing humans as well as animals. The disease can be caused by infection with a number of different serovars of the bacteria ''Leptospira interrogans''. In general infection with a host adapted strain results in subclinical infection, intermittent shedding of the organism with the animal acting as a reservoir for infection. Infection with non host adapted strains results in clinical disease. |
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| | + | Transmission is via urine of affected animals; the organism gains entry at mucous membranes, broken skin, bite wounds and through ingestion of infected material . The organism can remain viable for weeks in damp conditions |
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| − | ==Description==
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| − | Leptospirosis can be caused by infection with a number of different serovars of the bacteria Leptospira interrogans. In general infection with a host adapted strain results in subclinical infection, intermittent shedding of the organism and the animal acts as a reservoir for infection. Infection with non host adapted strains results in clinical disease.
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| | Vaccination against serovars ''canicola'' and ''icterohaemorrhagica'' has greatly reduced the prevalence and incidence of disease in the UK but in some areas the disease is re-emerging as owners decide not to vaccinate due to the reduced risk. Serovars ''pomona'' and ''grippotyphosa'' are becoming important. | | Vaccination against serovars ''canicola'' and ''icterohaemorrhagica'' has greatly reduced the prevalence and incidence of disease in the UK but in some areas the disease is re-emerging as owners decide not to vaccinate due to the reduced risk. Serovars ''pomona'' and ''grippotyphosa'' are becoming important. |
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| | ***Serovar ''bratislava'' causes abortion and infertility in dogs, which may be the maintenance host | | ***Serovar ''bratislava'' causes abortion and infertility in dogs, which may be the maintenance host |
| | *''Leptospirosis icterohaemorrhagica'' - a septicaemic disease which affects the [[Liver - Anatomy & Physiology|liver]] | | *''Leptospirosis icterohaemorrhagica'' - a septicaemic disease which affects the [[Liver - Anatomy & Physiology|liver]] |
| − | *puppies
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| − | *Leptospirosis is an important spirochaetal group of diseases causing disease in animals and humans (zoonotic)
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| − | *Transmission
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| − | **via urine of affected animals
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| − | **organisms can remain viable for weeks in damp conditions
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| − | *method of action
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| | **cause anaemia via intravascular haemolysis | | **cause anaemia via intravascular haemolysis |
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| | ==Signalment== | | ==Signalment== |
| − | Leptospirosis can affect dogs of any age, breed or sex. Young male, adult working dogs are at greatest risk. | + | Leptospirosis can affect dogs of any age, breed or sex. Young male, adult working dogs are at greatest risk. |
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| | ==Diagnosis== | | ==Diagnosis== |