Systemic signs are likely to indicate the development of [[Lungs Inflammatory - Pathology#Bronchopneumonia|bronchopneumonia]], signs include pyrexia, inappetance and depression. Systemic disease is more likely to occur in young or immunocompromised animals. This condition is usually a result of secondary infection with [[:Category:Pasteurella and Mannheimia species| ''Pasturella'' species]] and [[:Category:Streptococcus species|''Streptococci'' bacteria]]. If widespread systemic signs are present infection with canine distemper virus should be suspected. | Systemic signs are likely to indicate the development of [[Lungs Inflammatory - Pathology#Bronchopneumonia|bronchopneumonia]], signs include pyrexia, inappetance and depression. Systemic disease is more likely to occur in young or immunocompromised animals. This condition is usually a result of secondary infection with [[:Category:Pasteurella and Mannheimia species| ''Pasturella'' species]] and [[:Category:Streptococcus species|''Streptococci'' bacteria]]. If widespread systemic signs are present infection with canine distemper virus should be suspected. |