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==Description==  
 
==Description==  
Leptospirosis is an economically significant zoonotic disease caused by the bacteria [[Leptospira|''leptospira interrogans'']]. ''L. interrogans'' serovar ''hardjo'' is host-adapted to cattle; disease in cattle is usually due to ''L.pomona'' or ''L.hardjo''. Clinical disease is rarely seen in sheep, they are less susceptible to the bacterium but may act as non-symptomatic carriers.   
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Leptospirosis is an economically significant zoonotic disease caused by the bacteria [[Leptospira|''leptospira interrogans'']]. Disease in cattle is usually due to ''L.pomona'' or ''L.hardjo'';''L. interrogans'' serovar ''hardjo'' is host-adapted to cattle. Clinical disease is rarely seen in sheep, they are less susceptible to the bacterium but may act as non-symptomatic carriers.   
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In cattle leptospirosis is seen in 3 forms, acute, subacute and chronic. The acute disease is seen most frequently in calves, causing pyrexia, haemoglobinurea, jaundice, anorexia, uraemia due to renal damage and death. Acute disease in susceptible heifers, is seen as fever, lethargy, agalactia of all quarters; abortion and stillbirth may also occur. The subacute form results in clinical signs similar to those of the acute form, in a less severe form. The
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In the rare cases affecting sheep, infection results in an acute syndrome in lambs, or abortion and agalactia in ewes.
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In cattle leptospirosis is seen in 3 forms, acute, subacute and chronic.
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***Acute disease in susceptible heifers, with fever and agalactia of all quarters; abortion and stillbirth may occur
   
***Diagnosed by rising antibody titre in paired serum samples
 
***Diagnosed by rising antibody titre in paired serum samples
***Infection in sheep may cause abortion and agalactia
   
***Urinary excretion can be reduced by administering dihydrostreptomycin or amoxycillin
 
***Urinary excretion can be reduced by administering dihydrostreptomycin or amoxycillin
 
***Incactivated vaccines are of questionable efficacy
 
***Incactivated vaccines are of questionable efficacy
***Serovars ''pomona, grippotyphosa'' and ''icterohaemorrhagiae'' cause pyrexia, haemoglobinurea, jaundice, anorexia, uraemia due to renal damage and death in calves and lambs
      
==Signalment==
 
==Signalment==
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