− | Although FNI is rare, the mortality associated with the disease is high. Purebred cats are more commonly affected than domestic shorthair cats. Similarly to affected foals, kittens are born and nurse normally and clinical signs develop within a few hours or days. Signs may be variable and kittens are occasionally found dead within a few hours of the onset of clinical signs. Affected kittens rarely survive the first week of life. Clinical signs may include failure to thrive, weakness, dark red/brown urine, icterus, and anaemia. Affected kittens may separate themselves from the rest of the litter, stop nursing and appear weak. Signs may vary in severity within a single litter; this is thought to be related to differences in colostral intake. Other features of the disease may include necrosis and slouging of the tail tip and disseminated intravascular coagulation. | + | Although FNI is rare, the mortality associated with the disease is high. Purebred cats are more commonly affected than domestic shorthair cats. Similarly to affected foals, kittens are born and nurse normally and clinical signs develop within a few hours or days. Signs may be variable and kittens are occasionally found dead within a few hours of the onset of clinical signs. Clinical signs may include failure to thrive, weakness, dark red/brown urine, icterus, and anaemia. Affected kittens may separate themselves from the rest of the litter, stop nursing and appear weak. Signs may vary in severity within a single litter; this is thought to be related to differences in colostral intake. Other features of the disease may include necrosis and slouging of the tail tip and disseminated intravascular coagulation. Affected kittens rarely survive the first week of life. |
− | The disease in horses is prevented by ensuring that mares are blood-typed before being mated. Mares who are negative for the blood antigens known for causing disease (primarily Aa, Qa, Qc and Ua) can be matched to stallions who are also negative. Similarly in cats, the disease is easily prevented if blood typing of cats is beformed prior to breeding. | + | The disease in horses is prevented by ensuring that mares are blood-typed before being mated. Mares who are negative for the blood antigens known for causing disease can be matched to stallions who are also negative. Similarly in cats, the disease is easily prevented if blood typing of cats is beformed prior to breeding. |