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[[Image:LH Erythrocyte Histology.jpg|thumb|right|150px|<p>'''Erythrocytes'''</p>^{©RVC 2008}]]

 

[[Image:LH Erythrocyte Histology.jpg|thumb|right|150px|<p>'''Erythrocytes'''</p>]]

Also known as '''''red blood cells (RBCs)

Also known as '''''red blood cells (RBCs)

<p>Erythrocytes deliver oxygen to, and remove carbon dioxide from tissues.</p>

<p>Erythrocytes deliver oxygen to, and remove carbon dioxide from tissues.</p>

Erythrocytes are derived from the stem cell ([[Haematopoiesis - Overview#Colony Forming Units|CFU-GEMM]]) and formed in a process known as [[Erythropoiesis|erythropoiesis]].

Erythrocytes are derived from the stem cell ([[Haematopoiesis - Overview#Colony Forming Units|CFU-GEMM]]) and formed in a process known as [[Erythropoiesis|erythropoiesis]].

==Erythrocyte Structure==

==Erythrocyte Structure==

[[Image:LH_Avian_Erythrocyte_Histology.jpg|thumb|right|150px|<p>'''Avian Erythrocytes'''</p>.^{©RVC 2008}]]

[[Image:LH_Avian_Erythrocyte_Histology.jpg|thumb|right|150px|<p>'''Avian Erythrocytes'''</p>]]

===Mammals===

===Mammals===

<p>Erythrocytes are small (4-8µm), circular, anucleate biconcave cells that lack organelles. </p>

<p>Erythrocytes are small (4-8µm), circular, anucleate biconcave cells that lack organelles. </p>

==Function==

==Function==

RBCs contain haemoglobin, an oxygen binding protein that is responsible for the transport of oxygen from the lungs to tissues, and the transportation of carbon dioxide from the tissues to the lungs for elimination.

RBCs contain '''haemoglobin''', an oxygen binding protein that is responsible for the transport of oxygen from the lungs to tissues, and the transportation of carbon dioxide from the tissues to the lungs for elimination.

[[Image:LH Hb Animation.gif|thumb|right|250px|<p>Blue(α) & orange(β) are globin chains</p><p>Red objects represent haem groups</p>]]

[[Image:LH Hb Animation.gif|thumb|right|250px|<p>Blue(α) & orange(β) are globin chains</p><p>Red objects represent haem groups</p>]]

<p>Haemoglobin (Hb) is a metalloprotein that binds oxygen reversibly and accounts for almost all of the protein in the erythrocyte.</p>

<p>Haemoglobin (Hb) is a metalloprotein that binds oxygen reversibly and accounts for almost all of the protein in the erythrocyte.</p>

[[Image:Haem Breakdown.jpg|center|thumb|375px|<div style="text-align: center;"><p>'''Haem breakdown pathway'''</p>^{©Nottingham Uni 2008}</div>]]

[[Image:Haem Breakdown.jpg|center|thumb|375px|<div style="text-align: center;"><p>'''Haem breakdown pathway'''</p>^{©Nottingham Uni 2008}</div>]]

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[[Category:Blood Cells]]

 

 

 

 

 

[[Category:Blood Cells]] [[Category:Kate English reviewing]]