<p>To migrate through connective tissue they release proteases and glycoaminoglycanases.</p>
<p>To migrate through connective tissue they release proteases and glycoaminoglycanases.</p>
===Role in pathology===
===Role in pathology===
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<p>Macrophages are seen in both [[Acute Inflammation|acute]] and [[Chronic Inflammation| chronic inflammation]].</p> If large numbers of macrophages are found in chronic inflammatory processes, it implies the inability to eliminate the causal organism e.g. [[Respiratory Bacterial Infections - Pathology#Tuberculosis|Tuberculosis]], [[:Category:Actinobacillus species|''Actinobacilllus'']], fungi, parasites and foreign bodies.
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<p>Macrophages are seen in both [[Acute Inflammation|acute]] and [[Chronic Inflammation| chronic inflammation]].</p> If large numbers of macrophages are found in chronic inflammatory processes, it implies the inability to eliminate the causal organism e.g. [[:Category:Mycobacterium species|Mycobacterium (TB)]], [[:Category:Actinobacillus species|Actinobacillus]], fungi, parasites and foreign bodies.