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[[Image:LH Monocyte Histology.jpg|right|thumb|150px|<p>'''Monocyte'''</p><sup>©RVC 2008</sup>]]
[[Image:LH Monocyte Histology.jpg|right|thumb|150px|<p>'''Monocyte'''</p><sup>©RVC 2008</sup>]]
==Introduction==
==Introduction==
Monocytes are the largest [[Leukocytes|leukocytes]]. They have a large indented nucleus, few granules and constitute about 5% of circulating [[Leukocytes|leukocytes]]. Monocytes are precursors to a number of cells that make up the [[Lymphoreticular System - Anatomy & Physiology|mononuclear phagocytic system]]. Developing in the [[Bone Marrow - Anatomy & Physiology|bone marrow]], monocytes migrate into the circulation where, after approximately three days, they migrate into tissues and differentiate.
Monocytes are the largest [[Leukocytes|leukocytes]]. They have a large indented nucleus, few granules and constitute about 5% of circulating leukocytes. Monocytes are precursors to a number of cells that make up the [[Lymphoreticular System - Anatomy & Physiology|mononuclear phagocytic system]]. Developing in the [[Bone Marrow - Anatomy & Physiology|bone marrow]], monocytes migrate into the circulation where, after approximately three days, they migrate into tissues and differentiate.
==Development==
==Development==
<p>Monocytes develop from the bi-potential [[Haematopoiesis - Overview#Colony Forming Units|CFU-GM]] stem cell. Further details of this process ([[Leukopoiesis|leukopoiesis]]) can be found [[Leukopoiesis#Monocyte development|here]].</p>
<p>Monocytes develop from the bi-potential [[Haematopoiesis - Overview#Colony Forming Units|CFU-GM]] stem cell. Further details of this process ([[Leukopoiesis|leukopoiesis]]) can be found [[Leukopoiesis#Monocyte development|here]].</p>