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Image:LH_Avian_Thrombocyte_Histology.jpg|<center><p>'''Avian Thrombocytes'''</p><sup>©RVC 2008</sup></center></gallery>
Image:LH_Avian_Thrombocyte_Histology.jpg|<center><p>'''Avian Thrombocytes'''</p><sup>©RVC 2008</sup></center></gallery>
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''More commonly called platelets''
Commonly known as '''''platelets
==Introduction==
==Introduction==
Thrombocytes are small anuclear fragments of [[Thrombopoiesis#Megakaryocyte|megakaryocytes]]. They are membrane bound portions of the [[Thrombopoiesis#Megakaryocyte|megakaryocyte]] cytoplasm and have a finely granular cytoplasm that stains pink. They are much smaller than other blood cells at 2-3µm and have a lifespan of around 10 days in circulation.
Thrombocytes are small anuclear fragments of [[Thrombopoiesis#Megakaryocyte|megakaryocytes]]. They are membrane bound portions of the [[Thrombopoiesis#Megakaryocyte|megakaryocyte]] cytoplasm and have a finely granular cytoplasm that stains pink. They are much smaller than other blood cells at 2-3µm and have a lifespan of around 10 days in circulation.
<p>Thrombocytes play a number of roles in [[Haemostasis|haemostasis]]. They adhere to exposed connective tissue in the walls of blood vessels forming platelet plugs, while releasing a number of factors from their granules. The glycocalyx on their surface provides a surface for fibrinogen to convert to fibrin leading to the formation of the secondary haemostatic plug. The platelets then contract (see structural zone) reducing the clot size. Finally lytic enzymes are released to break the clot down.</p><p>If platelet numbers fall below 50x10<sup>9</sup>/l an animal is likely to haemorrhage after trauma and if the count falls below 30x10<sup>9</sup>/l then spontaneous haemorrhage is a risk.</p><p>PDGF from the granules stimulates tissue repair in blood vessels by stimulating smooth muscle cells and fibroblasts.</p>
<p>Thrombocytes play a number of roles in [[Haemostasis|haemostasis]]. They adhere to exposed connective tissue in the walls of blood vessels forming platelet plugs, while releasing a number of factors from their granules. The glycocalyx on their surface provides a surface for fibrinogen to convert to fibrin leading to the formation of the secondary haemostatic plug. The platelets then contract (see structural zone) reducing the clot size. Finally lytic enzymes are released to break the clot down.</p><p>If platelet numbers fall below 50x10<sup>9</sup>/l an animal is likely to haemorrhage after trauma and if the count falls below 30x10<sup>9</sup>/l then spontaneous haemorrhage is a risk.</p><p>PDGF from the granules stimulates tissue repair in blood vessels by stimulating smooth muscle cells and fibroblasts.</p>
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[[Category:Blood_Cells]]
[[Category:Blood_Cells]]