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Haematopoiesis - Overview (view source)
Revision as of 09:08, 28 September 2010
, 09:08, 28 September 2010no edit summary
[[Image:LH_Variety_blood_cells_Histology.jpg|right|thumb|200px|<p>'''Blood cells'''</p><sup>©RVC 2008</sup>]]
==Introduction==
==Introduction==
Also referred to as haemopoiesis or hemopoiesis and is the process of blood cell formation. All blood cells are derived from the initial pluripotent stem cell (PPSC) which gives rise to colony forming units (CFU). These CFU's further differentiate to give rise to the various blood cells found.
Also referred to as haemopoiesis or hemopoiesis and is the process of blood cell formation. All blood cells are derived from the initial pluripotent stem cell (PPSC) which gives rise to colony forming units (CFU). These CFU's further differentiate to give rise to the various blood cells found.
==Development==
==Development==
[[Image:LH_Avian_Variety_blood_cells_Histology.jpg|right|thumb|200px<p>'''Avian Blood cells'''</p><sup>©RVC 2008</sup>]]
Image:LH_Variety_blood_cells_Histology.jpg|<center><p>'''Blood cells'''</p><sup>©RVC 2008</sup></center>
<p>PPSC’s initially divide and differentiate into multipotential haematopoietic stem cells. Multipotential haematopoietic stem cells only have the ability to mature into a single cell lineage, either myeloid progenitors (granulocytes, erythroblasts, [[Macrophages|macrophages]] and megakaryocytes) or lymphoid progenitors. The development of blood cells from the multipotential haematopoietic stem cell into the final mature cell is categorised into:
<p>PPSC’s initially divide and differentiate into multipotential haematopoietic stem cells. Multipotential haematopoietic stem cells only have the ability to mature into a single cell lineage, either myeloid progenitors (granulocytes, erythroblasts, [[Macrophages|macrophages]] and megakaryocytes) or lymphoid progenitors. The development of blood cells from the multipotential haematopoietic stem cell into the final mature cell is categorised into:
* The formation of [[Erythrocytes|erythrocytes]] ([[Erythropoiesis|Erythropoiesis]])
* The formation of [[Erythrocytes|erythrocytes]] ([[Erythropoiesis|Erythropoiesis]])