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Also known as: '''''Bacillary Typhilitis
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Tyzzer's disease is caused by the obligatory intracellular ''Clostridium (formerly Bacillus) piliformis'', a gram-variable organism diagnosed on post-mortem examination by histopathology utilising Giemsa or Warthin-Starry staining techniques (Walden 1990). The organism may be seen on impression smears of the ileum lining (see Okerman 1994). The organism does not grow on broth or agar. Predisposing causes in rabbits are not known (Carman 1994) but weanlings are most frequently affected.  
 
Tyzzer's disease is caused by the obligatory intracellular ''Clostridium (formerly Bacillus) piliformis'', a gram-variable organism diagnosed on post-mortem examination by histopathology utilising Giemsa or Warthin-Starry staining techniques (Walden 1990). The organism may be seen on impression smears of the ileum lining (see Okerman 1994). The organism does not grow on broth or agar. Predisposing causes in rabbits are not known (Carman 1994) but weanlings are most frequently affected.  
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Treatment is not generally recommended but may be attempted (tetracyclines).  The disease has also been reported under circumstances which suggested that it may be spread by wild mice (MAFF monthly report 080892).
 
Treatment is not generally recommended but may be attempted (tetracyclines).  The disease has also been reported under circumstances which suggested that it may be spread by wild mice (MAFF monthly report 080892).
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==Literature Search==
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[[File:CABI logo.jpg|left|90px]]
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Use these links to find recent scientific publications via CAB Abstracts (log in required unless accessing from a subscribing organisation).
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<br><br><br>
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[http://www.cabdirect.org/search.html?q=%28title%3A%28%22Tyzzer%27s+disease%22%29+OR+title%3A%28%22Bacillary+Typhilitis%22%29+OR+title%3A%28%22Bacillus+piliformis%22%29+OR+title%3A%28%22Clostridium+piliforme%22%29%29+AND+od%3A%28rabbits%29 Tyzzer's disease/''Clostridium piliforme'' in rabbits]
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[[Category:Enteropathies_-_Rabbit]]
 
[[Category:Enteropathies_-_Rabbit]]
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