Changes

==Development==

==Development==

[[Erythrocytes|Erythrocyte]] development is divided into several stages and at each stage the cell will divide several times. As [[Bone Marrow - Anatomy & Physiology|bone marrow]] does not act as storage, all erythrocytes produced are immediately released into the circulation.

[[Erythrocytes|Erythrocyte]] development is divided into several stages and at each stage the cell will divide several times. As bone marrow does not act as storage, all erythrocytes produced are immediately released into the circulation.

===Stem cell ===

===Stem cell ===

[[Erythrocytes|Erythrocytes]] develop from stem cells that give rise to precursors which eventually mature to form the erythrocyte. The first erythrocyte precursor, the proerythroblast, is derived from the Erythroid CFU ([[Haematopoiesis - Overview#Colony Forming Units|CFU-E]]) which has differentiated from the multipotential myeloid stem cell ([[Haematopoiesis - Overview#Colony Forming Units|CFU-GEMM]]). This process is controlled and influenced by a number of different factors including erythropoietin, IL-3, IL-4 and granulocyte-macrophage colony stimulating factor (GM-CSF).

Stem cells give rise to precursors which eventually mature to form the fully developed erythrocyte.

Initially, the multipotential myeloid stem cell ([[Haematopoiesis - Overview#Colony Forming Units|CFU-GEMM]]) differentiates into the erythroid CFU ([[Haematopoiesis - Overview#Colony Forming Units|CFU-E]]). This develops into the first erythrocyte precursor, the proerythroblast.

The development process is controlled and influenced by a number of different factors including erythropoietin, IL-3, IL-4 and granulocyte-macrophage colony stimulating factor (GM-CSF).

===Nomenclature===

===Nomenclature===