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Thrombopoiesis is the process of formation of [[Thrombocytes|thrombocytes]] ([[Thrombocytes|platelets]]).
Thrombopoiesis is the process of formation of [[Thrombocytes|thrombocytes]] ([[Thrombocytes|platelets]]).
==Stages==
==Stages of Development==
[[Image:Thrombopoiesis_pathway.jpg|right|thumb|100px|'''Thrombopoiesis Pathway''']]
[[Image:Thrombopoiesis_pathway.jpg|right|thumb|125px|'''Thrombopoiesis Pathway''']]
===Stem Cell===
===Stem Cell===
As with [[Erythrocytes|erythrocytes]], [[Thrombocytes|thrombocytes]] are derived from multipotential myeloid stem cells ([[Haematopoiesis - Overview#Colony Forming Units|CFU-GEMM]]). In the [[Bone Marrow - Anatomy & Physiology|bone marrow]] CFU-GEMM cells differentiate into the megakaryocyte precursor cell the megakaryocyte CFU ([[Haematopoiesis - Overview#Colony Forming Units|CFU-Meg]]), under the influence of CFU-CSF and IL-3. Unlike other blood cells which undergo mitosis in the first few developmental stages, once the [[Haematopoiesis - Overview#Colony Forming Units|CFU-GEMM]] has differentiated into the [[Haematopoiesis - Overview#Colony Forming Units|CFU-Meg]] there is no further mitosis. The [[Haematopoiesis - Overview#Colony Forming Units|CFU-Meg]] then differentiates into the megakaryoblast.
As with [[Erythrocytes|erythrocytes]], [[Thrombocytes|thrombocytes]] are derived from multipotential myeloid stem cells ([[Haematopoiesis - Overview#Colony Forming Units|CFU-GEMM]]). In the [[Bone Marrow - Anatomy & Physiology|bone marrow]] CFU-GEMM cells differentiate into the megakaryocyte precursor cell the megakaryocyte CFU ([[Haematopoiesis - Overview#Colony Forming Units|CFU-Meg]]), under the influence of CFU-CSF and IL-3. Unlike other blood cells which undergo mitosis in the first few developmental stages, once the [[Haematopoiesis - Overview#Colony Forming Units|CFU-GEMM]] has differentiated into the [[Haematopoiesis - Overview#Colony Forming Units|CFU-Meg]] there is no further mitosis. The [[Haematopoiesis - Overview#Colony Forming Units|CFU-Meg]] then differentiates into the megakaryoblast.