Changes

*Inadequate haemostatic response. This may be caused by [[Platelet Abnormalities|platelet dysfunction or deficiency]], which leads to a primary or secondary thrombocytopenic purpura, or [[Coagulation Factor Deficiency|deficiencies/derangements of clotting factors]].

*Inadequate haemostatic response. This may be caused by [[Platelet Abnormalities|platelet dysfunction or deficiency]], which leads to a primary or secondary thrombocytopenic purpura, or [[Coagulation Factor Deficiency|deficiencies/derangements of clotting factors]].

Syndromes caused by vascular fragility and platelet dysfunction tend to be purpuric and acquired.

Generally, syndromes caused by vascular fragility and platelet dysfunction tend to be purpuric and acquired.

Syndromes caused by clotting factor defects tend to cause more severe bleeding and are usually congenital.

Syndromes caused by clotting factor defects tend to cause more severe bleeding and are usually congenital.