Changes

[[Platelet|Platelets]] (or thrombocytes) are responsible for primary haemostasis by the formation of a temporary platelet plug that initially seals any breach to a blood vessel wall.  These breaches are then sealed more completely by the formation of a fibrin clot induced by the coagulation factor cascade.   

[[Platelet|Platelets]] (or thrombocytes) are responsible for primary haemostasis by the formation of a temporary platelet plug that initially seals any breach to a blood vessel wall.  These breaches are then sealed more completely by the formation of a fibrin clot induced by the coagulation factor cascade.   

===Terminology===

===Terminology===

*'''Thrombocytopaenia''' refers to low absolute numbers of platelets. [[Immune Mediated Thrombocytopaenia|Immune-mediated thrombocytopaenia]] (ITP) is one common cause of thrombocytopaenia and this may be a primary or secondary disease.   

*'''Thrombocytopaenia''' refers to low absolute numbers of platelets. Infections, neoplasia and [[Immune Mediated Thrombocytopaenia|Immune-mediated thrombocytopaenia]] (ITP) are common causes of thrombocytopaenia, which is frequently a secondary disease.   

*'''Thrombocytopathia''' refers to platelets that are unable to function adequately.

*'''Thrombocytopathia''' refers to platelets that are unable to function adequately.

*'''Thrombocytosis''' refers to an increase in the blood platelet concentration above the normal level.

*'''Thrombocytosis''' refers to an increase in the blood platelet concentration above the normal level.