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Guinea Pigs (Laboratory) - Pathology (view source)
Revision as of 13:00, 22 October 2010
, 13:00, 22 October 2010no edit summary
===Adenovirus===
===Adenovirus===
Adenoviridae do not require co-infection with bacteria in order to become pathogenic within the respiratory system. The infection may have no clinical symptoms but in susceptible animals such as those that are stressed or immune-deficient it can be fatal.
Adenoviridae do not require co-infection with bacteria in order to become pathogenic within the respiratory system. The infection may have no clinical symptoms but in susceptible animals such as those that are stressed or immune-deficient it can be fatal.<br />
===Digestive System===
==Infectious Causes of Diarrhoea==
'''Salmonella'''
Salmonella typhimurium and Salmonella enteriditis are the common causative agents and are often associated with contaminated food and bedding. Diarrhoea may be haemorrhagic, cause septicaemia and can also cause sudden death. Diagnosis is via isolation and culture of the Salmonella spp via faecal samples.<br />
Chronic cases and those that recover from a Salmonella infection are likely to become carriers and should be destroyed to prevent further outbreaks. <br />
'''Yersinia (pseudotuberculosis)'''
Acute forms of this disease can cause septicaemia and death within 48hrs. Chronic cases have more progressive clinical symptoms but will usually culminate in death after 3-4 weeks. During this 3-4 week period any young may become congenitally or neonatally affected. Diagnosis is via culture of Yersinia pseudotuberculosis from blood, lymph nodes or faecal samples.<br />
Yersinia infections are transmitted via wild birds and other rodents contaminating their food, particularly green foods. Once the disease is endemic in a breeding population some infections can be passed vertically in the milk. <br />
'''Clostridia'''
Normally this species are present in the large intestines as commensals but during certain circumstances such as antibiotic administration they are able to proliferate and cause fatal enterotoxaemia. Clostridium species can be cultured from the lumen of the infected intestine.