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→Arterial
*shows 'apple-green' fluorescence under polarised light after staining with Congo Red
*shows 'apple-green' fluorescence under polarised light after staining with Congo Red
==Arterial==
==Arterial Dissemination==
Amyloid is an eosinophilic, homogenous, hyaline material. Due to its beta-pleated-sheet structure it is almost insoluble. Amyloid may be present in one of two forms:
Amyloid is an eosinophilic, homogenous, hyaline material. Due to its beta-pleated-sheet structure it is almost insoluble. Amyloid may be present in one of two forms:
*'''AA''': Serum amyloid A, alpha-2 globulin.
*'''AA''': Serum amyloid A, alpha-2 globulin.
Disease may be truly idiopathic (dogs and cats) or may be secondary to another disease process, often chronic inflammation or neoplasia. Chronic antigenic stimulation induces the overproduction of AA protein which may become deposited throughout the body.
Disease may be truly idiopathic (dogs and cats) or may be secondary to another disease process, often chronic inflammation or neoplasia. Chronic antigenic stimulation induces the overproduction of AA protein which may become deposited throughout the body.
Deposits are found in:
Deposits can be found in:
*Renal vessels and glomeruli.
*Renal vessels and glomeruli.
*Splenic white pulp.
*Splenic white pulp.