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==Phosphorus==
[[Category:Lizard_and_Snake_Glossary]]
Phosphorus is the third most abundent intracellular ion:
#Potassium
#Magnesium
#Phosphorus (as Phosphate)
Within the body it is found as Phosphate ions or Phosphate within bone.
The majority (~95%) is combined with Calcium in bone, forming Hydroxyapatite. Less than 1% is found in the extracelullar fluid.
==Homeostasis==
Serum concentrations of phosphorus are maintained by dietary sources. It is absorbed across the intestine via ''Passive diffusion'' and ''[[Calcium#Calcitriol (Active Vitamin D3)|Vitamin D]] mediated active transport''.
Phosphorus is excreted in the urine or saliva (particularly in ruminants).
===Hormonal Regulation===
[[Calcium#Parathyroid Hormone (PTH)|'''PTH''']]
*Mobilises phosphorus from bone, acting to increase plasma concentration of P
*Increases phosphorus loss in the urine and saliva, acting to decrease plasma concentration
So ultimately, PTH acts to remove phosphorus from the body entirely.
[[Calcium#Calcitriol (Active Vitamin D3)|'''Calcitriol''']]
*Increases phosphorus absorbtion from the intestines
==Pathology==
Diseases relating to phosphorus homeostasis include:
*[[Bones Metabolic - Pathology#Primary hyperparathyroidism |Primary and Secondary Hyperparathyroidism]]
*[[Kidney Renal Failure - Pathology#Uraemia |Hyperphosphataemia]]
*Hypophosphatemia
==Test yourself with the Phosphorus Homeostasis Flashcards==
[[Phosphorus_Homeostasis_Flash_Cards_-_Anatomy_%26_Physiology|Phosphorus Homeostasis Flashcards]]
[[Category:Endocrine System - Anatomy & Physiology]]
[[Category:Electrolytes]]