6,273
edits
Changes
Jump to navigation
Jump to search
Guinea Pigs (Laboratory) - Pathology (view source)
Revision as of 20:54, 6 November 2010
, 20:54, 6 November 2010→Scurvy
The diet should have a calcium:phosphorus ratio of 1:5 and the same vitamin D level as above. <br />
The diet should have a calcium:phosphorus ratio of 1:5 and the same vitamin D level as above. <br />
===Scurvy===
===Scurvy===
This condition is due to a deficiency of vitamin C where an adult guinea pig requires 10-30mg per day. Haemorrhages will be found around joints and on all serosal surfaces. Clinical signs range from an unsteady gait, painful locomotion and bleeding gums.<br />
This condition is due to a deficiency of vitamin C where an adult guinea pig requires 10-30mg per day.
<br />
Macroscopic pathology will include haemorrhages around joints and on all serosal surfaces, particularly around fascial and articular cartilages. Petechial and ecchymotic bleeding may be seen on the periosteum, muscle and gingiva.<br />
Necropsy findings may include fascial and articular cartilage hemorrhages, petechial and ecchymotic bleeding on periosteum, muscle, and gingiva.
===Osteoarthritis===
===Osteoarthritis===
In guinea pigs the most commonly affected joint is the stifle and clinical symptoms can range from lameness to weight loss in guinea pigs of 9 months and older.<br />
In guinea pigs the most commonly affected joint is the stifle and clinical symptoms can range from lameness to weight loss in guinea pigs of 9 months and older.<br />