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The clinical symptoms of pneumonia include dyspnoea, ruttling (see above), sneezing, nasal discharge and coughing. If left untreated, guinea pigs can become depressed anorexic and it can become a fatal infection. In guinea pigs pneumonia can be caused be various bacterial and viral agents including ''Bordetella bronchiseptica, Streptococcus zooepidemicus, Streptococcus pneumonia, Klebsiella pneumonia, Pseudomonas aeruginosa and Pasturella spp.''<br />
 
The clinical symptoms of pneumonia include dyspnoea, ruttling (see above), sneezing, nasal discharge and coughing. If left untreated, guinea pigs can become depressed anorexic and it can become a fatal infection. In guinea pigs pneumonia can be caused be various bacterial and viral agents including ''Bordetella bronchiseptica, Streptococcus zooepidemicus, Streptococcus pneumonia, Klebsiella pneumonia, Pseudomonas aeruginosa and Pasturella spp.''<br />
 
Diagnosis is via isolation of the causal agent from a culture of the nasal discharge.<br />
 
Diagnosis is via isolation of the causal agent from a culture of the nasal discharge.<br />
'''''Bordetella'' Pathology''': Bordatella has an affinity from ciliated respiratory epithelium. Necropsy may reveal mucopurulent rhinitis, purulent bronchitis and tracheitis. Exudate can also be found in the tympanic bullae. There may also be pulmonary consolidation (usually anterioventral). Pleuritis or pyosalpinx may be seen.<br />
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'''''Bordetella'' Pathology''': Bordatella has an affinity for ciliated respiratory epithelium. Necropsy may reveal mucopurulent rhinitis, purulent bronchitis and tracheitis. Exudate can also be found in the tympanic bullae. There may also be pulmonary consolidation (usually anterioventral). Pleuritis or pyosalpinx may be seen.<br />
 
Microscopic pathology may include acute to chronic suppurative bronchopneimonia with heterophilic infiltration. There will also be generalised obliteration of the normal architecture together with fibrinous exudate.
 
Microscopic pathology may include acute to chronic suppurative bronchopneimonia with heterophilic infiltration. There will also be generalised obliteration of the normal architecture together with fibrinous exudate.
 
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